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Jessica Siegel

Associate Professor


  • Education
  • Academic History

    PhD, Behavioral Neuroscience, Oregon Health & Science University, 2011

    B.A., Psychology, The University of Puget Sound, 2006

    Jessica Siegel’s research examines the long-term effects of methamphetamine exposure on the brain and behavior using a mouse model. She is currently exploring the effects of adolescent methamphetamine exposure on brain function and behavior, specifically examining the dopamine transporters in the striatum and serum cortisol levels. She is also interested in how other drugs, such as nicotine, interact with the effects of methamphetamine in the adolescent brain. She teaches Brain & Human Behavior and Drugs & Behavior in the Psychology Department, and Principles of Neuroscience and Neuropharmacology in the Neuroscience Program.

  • Expertise
  • Expertise

    Behavioral neuroscience


Ortman, H.A. & Siegel, J.A. (2020). The effect of methadone on the hypothalamic pituitary gonadal axis and sexual function: a systematic review. Drug & Alcohol Dependence, 207, 1-17.

Struntz, K.H. & Siegel, J.A. (2018). Effects of methamphetamine exposure on anxiety-like behavior in the open field test, corticosterone, and hippocampal tyrosine hydroxylase in adolescent and adult mice. Behavioural Brain Research, 348, 211-218.

Baker, E.P., Magnuson, E.C., Dahly, A.M., & Siegel, J.A. (2018). The effects of enriched environment on the behavioral and corticosterone response to methamphetamine in adolescent and adult mice. Developmental Psychobiology, 60, 664-673.

Buck, J.M., Morris, A.S., Weber, S., Raber, J. & Siegel, J.A. (2017). Effects of adolescent methamphetamine and nicotine exposure on behavioral performance and MAP-2 immunoreactivity in the nucleus accumbens of adolescent mice. Behavioural Brain Research, 323, 78-85.

Rud, M.A., Do, T.N., & Siegel, J.A. (2016). Effects of early adolescent methamphetamine exposure on anxiety-like behavior and corticosterone levels in mice. Neuroscience Letters, 633, 257-261.

Buck, J.M. & Siegel, J.A. (2015). The effects of adolescent methamphetamine exposure. Frontiers in Neuroscience, 9, 1-5.

Joca, L., Zuloaga, D.G., Raber, J., & Siegel, J.A. (2014). Long-term effects of early adolescent methamphetamine exposure on depression-like behavior and the hypothalamic vasopressin system in mice. Developmental Neuroscience, 36 (2), 108-118.

Zuloaga, D.G., Siegel, J.A., Acevedo, S.F., Agam, M., & Raber, J. (2013). Developmental methamphetamine exposure results in short- and long-term alterations in HPA axis-associated proteins. Developmental Neuroscience, 35, 338-346.

Daniell, C., *Bartlett, S., & Siegel, J.A. (2013). Effects of high-fat diet and ethanol on cognition and behavior in mice. Journal of Young Investigators, 25 (7), 96-100.

Siegel, J.A., Park, B.S., & Raber, J. (2011). Methamphetamine exposure during brain development alters the brain acetylcholine system in adolescent mice. Journal of Neurochemistry, 119, 89-99.

Siegel, J.A., Park, B.S., & Raber, J. (2011). Long-term effects of neonatal methamphetamine exposure on cognitive function in adolescent mice. Behavioral Brain Research, 219 (1), 159-164.