- Popescu, C. V.; Dinh, T.; Chen, H.; Miller, D.; Washburn, A.; McGuire, A.; Dumarieh, R.; D'Antonio, J.; Ghiladi, R. A., Mössbauer studies of the ferryl, ferrous, and ferric states of the dehaloperoxidase from A. ornata. J. Inorg. Biochem. 2022, 234, 111867.
- Wang,P., Saber, M., VanNatta, P., Yap, G., Popescu, C.V., Scarborough, C., Kieber-Emmons, M., Dunbar, K., Riordan, C. G. "Molecular and electronic structures, and single-molecule magnet behavior of tris(thioether)-iron complexes containing redox-active α-diimine ligands" Inorg. Chem. (2021) 60 (9) 6480-6491. DOI: 10.1021/acs.inorgchem.1c00214
- Ekanayake, D.E, Fischer, A.A, *Elwood, M.E, Guzek, A.M, Lindeman, S.V, Popescu, C.V., Fiedler, A.T. "Nonheme Iron-Thiolate Complexes as Structural Models of Sulfoxide Synthase Active Sites" Dalton Trans. (2020) 49, 17745-17757. DOI: 1039/D0DT03403G (*Maya Elwood is an undergraduate student)
- Fontenot, C.R., Tasnim, H. *Valdes, K.A., Popescu, C.V., Ding, H. "Ferric uptake regulator (Fur) reversibly binds a [2Fe-2S] cluster to sense intracellular iron homeostasis in Escherichia coli" Biol. Chem. (2020) 295, 15454-15463. DOI: doi.org/10.1074/jbc.RA120.014814 (*Kate Valdes is an undergraduate student) EDITOR'S PICK!
- Kephart, J.A., Hecht, Z.H., Livesay, B.N., Shores, M.P., Popescu, C.V., Arulsamy, N., Hulley, E.B."Self-assembly of an Organometallic Fe₉O₆ Cluster from Aerobic Oxidation of (tmeda)Fe(CH₂tBu)₂" Chem. Comm. (2020) 56 (37) 4994-4997. DOI: 10.1039/D0CC00011F
- Gordon, Z., Miller, .T.J., Leahy, C.A., Matson, E.M., Burgess, M., Drummond, M.J., Popescu, C.V., *Smith, C.M., Lord, R.L., Rodríguez-López, J., Fout, A.R. Chem. (2019) Inorg. Chem. (2019) 58 (23) 15801–15811. DOI: 10.1021/acs.inorgchem.9b02079. (*Connor Smith is an undergraduate student)
- Popescu, C.V., Ding, S., Ghosh, P., Hall, *Cohara, M. Mössbauer Spectroscopic and Theoretical Studies of bimetallic complexes showing electrocatalytic hydrogen evolution Chem. (2019) 58 (10) 7069-7077. DOI: 10.1021/acs.inorgchem.9b00746. (*Morgan Cohara was an undergraduate student)
- Drummond, M. J., Ford, C. J., Gray, D. G., Popescu, C. V., Fout, A. R. Radical Rebound Hydroxylation Versus H-Atom Transfer in Non-Heme Iron(III)-Hydroxo Complexes: Reactivity and Structural Differentiation Am. Chem. Soc. (2019) 141 (16), 6639–6650. DOI: 10.1021/jacs.9b01516.
- Wang, P.; Killian, M.; Saber, M.; Qiu, T.; Yap, G.; Popescu, C. V.; Rosenthal, J.; Dunbar, K. R.; Brunold, T.; Riordan, C.G. “Electronic, Magnetic, Redox Properties and O2 Reactivity of Fe(II) and Ni(II)-o-Semiquinonate Complexes of a Tris(thioether) Ligand: Uncovering the Intradiol Cleaving Reactivity of an Fe(II)-o-semiquinonate Complex” Chem. (2017) 56 (17), 10481–10495; DOI: 10.1021/acs.inorgchem.7b01491.
- Prokopchuk, D.E., Wiedner, E.S, Walter, E.D., Popescu, C.V., Piro, N.A., Kassel, W.S.A., Bullock, M, Mock, M. T. Structure and reactivity of Iron Coordination Complexes toward Dinitrogen “Catalytic N2 Reduction into Silylamines and Thermodynamics of N2 Binding at Square Planar Fe” Am. Chem. Soc. (2017),139, 9291–9301; DOI: 10.1021/jacs.7b04552.
- Tichnell, C. R., Shultz, D. A. Popescu, C.V., *Sokirnyi, I, Boyle, P.D. “Synthesis, Characterization and Photophysical Studies of an Iron(III) Catecholate-Nitronylnitroxide Spin-Crossover Complex” I Chem. (2015) 54 (9), 4466–4474.
- Bittner, M.M., Lindeman, S.V., Popescu, C.V., Fiedler, T “Dioxygen Reactivity of Biomimetic Fe(II) Complexes with Noninnocent Catecholate, o-Aminophenolate, and o-Phenylenediamine Ligands” Inorg. Chem. (2014), 53 , 4047-4061.
- Hsieh, C.H.; Erdem, O.; Ding, S.; Crouthers, D.; Lubitz, W.; Popescu, C.V.; Reibenspies, J.; Hall, M. B. Darensbourg, M. Y. “Redox active iron nitrosyl units in proton reduction electrocatalysis” Nature Communications (2014) 5, 3684.
- Stoian, S., Hsieh, C.-H.;* Casuras, A.; Singleton, M.L., Darensbourg, M.Y., *McNeely, K.M., *Sweely, K., Popescu, C.V. “Hyperfine Interactions and Electron Distribution in FeIIFeI and FeIFeI Models for the Active Site of the [FeFe]-Hydrogenases”, Biol. Inorg. Chem., (2013) 18: 609-622 http://link.springer.com/article/10.1007/s00775-013-1005-5#page-1}
- Hsieh, C.-H.; Brothers, S.M.; Hall, M.B.; Popescu, C.V.; Darensbourg, M.Y., “The Ambidentate Thiocyanate Ligand in Dinitrosyl Iron Complexes”, Chem. (2013), 52(4): 2119-2124.
- Bittner, M.M., *Kraus, D., Lindeman, V., Popescu, C.V., Fiedler, A.T “Synthetic, Spectroscopic, and DFT Studies of Iron Complexes with Iminobenzo(semi)quinone Ligands: Implications for o-Aminophenol Dioxygenases” Chem. Eur. J. (2013), 19(29): 9686-98
- Hsieh, C.-H., Harman, S. D., Singleton, M.L., Reijersee, E.; Lubitz, W.; Popescu, C.V., Brothers, S.M., Reibenspies, J.H., Hall, M.B., Darensbourg, M.Y. "Structural and Spectroscopic Features of Mixed Valent FeIIFeI Complexes and Factors Related to the Rotated Configuration of Diiron Hydrogenase” Am. Chem. Soc. (2012), 134, 13089-13102.
- Liu, T., Li, B., Popescu, C.V., *Bilko, A., Perez, L., Hall, M. B., Darensbourg, M, Y. “Analysis of an Iron Dicarbonyl as Synthetic Analogue of the Hmd or [Fe]-Hydrogenase Active Site” Eur. J. (2010), 16, 3083-3089.
- Popescu, C.V., Mock, M.T., Stoian, S.A., Riordan, C.G. “A high-spin organometallic Fe-S compound: Structural and Mössbauer Spectroscopic Studies of [Phenyltris((tert-butylthio)methyl)borate]Fe(Me), Chem. (2009) 48 (17), 8317-8324.
- Li, B., Liu, T., Popescu, C.V., *Bilko, A., Darensbourg, M, Y. “Synthesis and Mössbauer Characterization of Octahedral Iron(II) Carbonyl Complexes FeI2(CO)3L and FeI2(CO)2L2: Developing Models of the [Fe]-H2ase Active Site” Inorganic Chemistry (2009), 48 (23), 11283-11289.
- Mock, M.T., Kieber-Emmons, M.T., Popescu, C.V., *Gasda, P., Yap, G.P.A., Riordan, C.G. “A Series of Cyanide-Bridged Binuclear Complexes”, Chim. Acta (2009) 362, 4553-4562.
- Mock, M.T., Popescu, C.V., Yap, G.P.A., Dougherty, W.G., Riordan, C.G. “Monovalent Iron In a Sulfur-rich Environment”, Chem. (2008), 47 (6), 1889-1891.
- Zhang, J., Wallar, B.J., Popescu, C.V., Renner, D.B, Thomas, D.D., Lipscomb, J.D. “Methane Monooxygenase Hydroxylase and B Component Interactions” Biochemistry 2006 45, 2913-2926.
- Wolfe, M. D., Altier, D. J., Stubna, A., Popescu, C. V., Münck, E., Lipscomb, J. D. “Benzoate 1,2-Dioxygenase from Pseudomonas putida: Single Turnover Kinetics and Regulation of a Two Component Rieske Dioxygenase”, Biochemistry 2002, 41(30), 9611-9626.
- Popescu, C. V., Münck, E., Fox, B. G, Sanakis, Y., Cummings, J. G., Turner, I. M., Jr., Nelson M. J. “Mössbauer and EPR Studies of the Photoactivation of Nitrile Hydratase”, Biochemistry 2001, 40, 7984-7991.
- Münck, E., Popescu, C. V. “Mössbauer Studies of Exchange Coupled Cluster Assemblies in Biological Systems” Hyperfine Interactions 2000, 126, 59- 67.
- Bates, D. M., Popescu, C. V., Koroshilova, N.; Vogt, K., Beinert, H. Münck, E., Kiley, P. J. “Substitution of Lucine 28 for Histidine in the E. coli Transcription Factor FNR Results in Increased Stability of the [4Fe-4S]2+ Cluster to Oxygen”, Biol. Chem. 2000, 275, 6234.
- Popescu, C. V., Münck, E. “On the electronic structure of the H-cluster in [Fe]-Hydrogenases”, Am. Chem. Soc. 1999, 121, 7877.
- Popescu, C. V., Bates, D. M., Beinert, H., Münck, E., Kiley, P. J. (1999) “Mössbauer studies of the FNR transcription factor in whole E. Coli cells”, in Iron Metabolism, Wiley-VCH
- Kyritsis, P., Kümmerle, R., Huber, J. G., Gaillard, J., Guigliarelli, B., Popescu C. V., Münck, E., Moulis, J. -M. “Unusual NMR, EPR, and Mössbauer Properties of Chromatium vinosum 2[4Fe-4S] Ferredoxin”, Biochemistry 1999, 38, 6335.
- Popescu, C. V., Bates, D. M., Beinert, H., Münck, E., Kiley, P. J. (1999) “Mössbauer studies of the FNR transcription factor in whole Coli cells”, in Iron Metabolism, Wiley-VCH.
- Popescu, C. V., Bates D. M., Münck E., Beinert, H., Kiley, P. J. “Mössbauer Spectroscopy as a Tool for the Study of Activation/Inactivation of the Transcription regulator FNR in whole Cells of Escherichia coli”, Nat. Acad. Sci. USA 1998, 95, 13431.
- Kauffmann, K., Popescu, C. V., Dong, Y., Lipscomb, J. D., Que, L. Jr, Münck, E. “Mössbauer Evidence for Antisymmetric Exchange in a Diferric Synthetic Complex and Diferric Methane Monooxygenase”, Am. Chem. Soc. 1998, 120, 8739.
- Hsu, H., Koch, S. A., Popescu, C. V., Münck, E. “Chemistry of Fe Thiolate Complexes with CN- and CO. Models for the [Fe(CO)(CN)2] Structural Unit in Ni-Fe Hydrogenase Enzymes”, Am. Chem. Soc. 1997, 119, 8371.
- Khoroshilova, N., Popescu, C. V., Münck, E., Beinert, H., Kiley, P. J. “Iron-sulfur cluster disassembly in the FNR protein of Escherichia coli by O2: [4Fe-4S] to [2Fe-2S] conversion with loss of biological activity”, Natl. Acad. Sci USA 1997, 94, 6087.
- Xia, J., Hu, Z., Popescu, C. V., Lindahl, P. A., Münck, E. “Mössbauer and EPR Study of the Ni-Activated Metallosubunit of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum”, Am. Chem. Soc. 1997, 119, 8301.
The ACS National Meeting – April 5 - 16, 2021, Virtual Meeting; Mössbauer Studies of Model Complexes for Short-Lived Intermediates of Cysteine Dioxygenases. Popescu, C. V., *Maya Elwood, *Anastasia Washburn, Praveen Kumar and Adam Fiedler.
ICBIC 19, The International Conference on Biological Inorganic Chemistry – 2019, Interlaken, Switzerland; Mössbauer studies of model complexes for intermediates in the catalytic cycle of mononuclear non-heme iron dioxygenases. Popescu, C. V., Fiedler, A., Kumar, P., Valdes, K.A.
The 53rd Midwest Regional Meeting of the American Chemical Society –October 2018, Ames, IA, MWRM-169; Mössbauer Studies of Mitochondrial and prokaryotic iron-sulfur proteins. Valdes, K., Popescu, C. V., Ding, H.
The 253rd ACS National Meeting –August 2017,San Francisco; Mössbauer Spectroscopy of Iron- Selone and and Iron-Thione Complexes Capable of Preventing Oxidative DNA Damage. Popescu, C. V.; *Morgan Cohara; Stadelman, B.; Brumaghim, J.
EUROBIC 13, The European Biological Inorganic Chemistry Conference – 2016, Budapest, Hungary; Mössbauer and Theoretical Studies of Bimetalic Complexes containing Metal-Nitroxide units. Popescu, C. V.; Shengda Ding; Pokhraj Gosh; Marcetta Y. Darensbourg.
Bucknell University, The Chemistry Seminar Series – March 29, 2016, Lewisburg, PA, Mössbauer Studies of Iron Complexes with Hydrogen-Evolving Activity. Popescu, C. V.
Colgate University – The Natural Sciences Division Colloquium, Spring 2016 – Analyzing Molecules with Mössbauer Spectroscopy to reveal Iron’s Catalytic Power. Popescu, C.V.
The 251st ACS National Meeting – San Diego, 2016; Mössbauer Spectroscopy and Electronic Structure of Iron-Nitrosyl Complexes. Popescu, C. V.; Pokhraj Gosh; *Morgan Cohara; Marcetta Y. Darensbourg.
The 250th ACS National Meeting – Boston, August, 2015; Mössbauer Studies of multimetallic assemblies of complexes with different spin states. Popescu, C. V.; Pokhraj Gosh; *Kaye Kuphal; *Nicholas Baglieri; Marcetta Y. Darensbourg.
The 248th ACS National Meeting – San Francisco, August, 2014; Mössbauer Studies of the ferryl, ferrous, and ferric states of the dehaloperoxidase from Amphitrite ornata. Popescu, C. V.; Barrios, David; *Miller, Danielle B.; Ghiladi, Reza A.
The 248th ACS National Meeting – San Francisco, August, 2014; Mössbauer Studies of a low-spin monovalent iron complex; Popescu, C. V.; Wang, P.; *DeHont, Raymond; Mock, Michael T.; Riordan, Charles G.
The 248th ACS National Meeting – San Francisco, August, 2014; Mössbauer and Magnetometry Studies of a ferric complex with spin transition. Popescu, C. V.; *Sokirnyi, Ivan; Tichnell, Christopher; Shultz, David.
The 247th ACS National Meeting – Dallas, March, 2013; Mössbauer Studies of the dual-function protein Dehaloperoxidase. Popescu, C. V., *Danielle Miller, Reza Ghiladi
The International Conference on Biological Inorganic Chemistry – ICBIC 16 – Grenoble, France, July 21-26, 2013: Hyperfine Interactions in the 2Fe subcluster of the [Fe-Fe] hydrogenases. Popescu, C. V., S. Stoian, *A. Casuras, C.-H. Hsieh, M. Singleton, M. Y. Darensbourg.
The 244th ACS National Meeting – Philadelphia, PA August 19-23, 2012; Mössbauer Studies of mixed-valence FeIIFeI and FeIFeI model complexes illustrating states of the H-cluster in the [Fe-Fe]-hydrogenases. C. V. Popescu, S. Stoian, A. Casuras, C.-H. Hsieh, M. Singleton, M. Y. Darensbourg.(INOR-49)
The 244th ACS National Meeting – Philadelphia, PA August 19-23, 2012; Mössbauer Studies of model complexes for the [Fe-Fe]-hydrogenases: Electronic Structure of Mixed-Valent Complexes Containing Low-Spin FeI. C. V. Popescu, S. Stoian, A. Casuras, C.-H. Hsieh, M. Singleton, M. Y. Darensbourg. (INOR-699)
The 244th ACS National Meeting – Philadelphia, PA August 19-23, 2012; Mössbauer Studies of the enzyme dehaloperoxidase from A. ornata. D. Miller, C. V. Popescu, J. Birabaharan, R. Dumarieh, R. Ghiladi. (CHED-178)
Gordon Research Conference: Iron-Sulfur Enzymes, Mount Holyoke College, Massachusetts, June 10-14, 2012: Mössbauer Studies of Low-spin Monovalent Iron and the Mixed-Valence Fe(II)Fe(I) Oxidized state of the [Fe-Fe]-Hydrogenases, C. V. Popescu, S. Stoian, A. Casuras, C.-H. Hsieh, M. Singleton, M. Y. Darensbourg.
"The Villanova University Physics Colloquium", February 12, 2012 - "Mössbauer studies of monovalent iron in search for a good model for the hydrogenase" C. V. Popescu.
The International Conference on Biological Inorganic Chemistry – ICBIC 15 – Vancouver, Canada, August 6 – 13, 2011; "Mössbauer studies of model complexes illustrating different states of the H-cluster in [Fe-Fe] hydrogenases" C. V. Popescu, S. Stoian, A. Casuras, M. Singleton, M. Y. Darensbourg.
The 239th ACS National Meeting – Boston, MA, August 16-20, 2010; "Advances in the characterization of discrete states of the hydrogenase active site" C. V. Popescu, A. Bilko, M. Singleton, M. Y. Darensbourg.
Gordon Research Conference: Iron-Sulfur Enzymes, Colby-Sawyer College, New Hampshire, June 6-11, 2010; "Mössbauer studies of model complexes for the active site of the Fe-only hydrogenases" C. V. Popescu, Marcetta Darensbourg, Michael Singleton, Andrey Bilko.
The 238th ACS National Meeting – Washington, D.C., August 16-20, 2009;
“Mössbauer Studies of a high-spin ferrous organometallic complex”, C. V. Popescu,M. T. Mock, S. A. Stoian, C. G. Riordan.
The International Conference on Biological Inorganic Chemistry – ICBIC 13 – Vienna, Austria, July 15 – 22, 2007. “Synthetic, structural and Mössbauer studies of novel high-spin iron complexes supported by a tri-thioether ligand” - C. V. Popescu, M. Mock, S. A. Stoian and C. G. Riordan.
The National CUR Conference – De Pauw, Indiana, June 22-26, 2006; “Mössbauer spectroscopy: challenge and opportunity for undergraduate researchers” – C.V. Popescu, Michael Mock, Charles Riordan.
The Bryn Mawr - Haverford Chemistry Colloquium, October 28, 2005 - "Mössbauer studies of model compounds for the active sites of hydrogenases and Carbon Monoxide Dehydrogenase" Popescu, C. V.
International Conference on Biological Inorganic Chemistry – ICBIC 12 – Ann Arbor, Michigan, July 31-August 5, 2005; Poster: Mössbauer studies of the effects of ligand binding and redox changes in the active center of the [NiFe]-hydrogenase from Allochromatium vinosum - Popescu, C. V., Surerus, K. K., Ravi, N., Duin, E., Roseboom, W., Münck, E. and Albracht, S.P.J.
The 228th ACS National Meeting - Philadelphia, August 22-26, 2004; “57Fe - Mössbauer spectroscopic studies of model compounds for the Fe-only hydrogenases”, DeHont, R. F.; Chiarella, G.; Melgarejo, D.; Stoian, S.; Koch, S.; Münck, E.; Popescu, C. V.
The National CUR Conference – La Crosse, Wisconsin, June 16-22, 2004 – “Fluorescence and Mössbauer spectroscopic studies of biologically relevant systems” – C.V. Popescu, Raymond DeHont.
The 10th International Workshop in ESR Spectroscopy and Imaging – April 2003, Fukuoka, Japan – “Mutagenesis and ESR studies of the component interactions in the methane monooxygenase from M. trichosporium” Popescu, C.V., Cornea, R. L., Lipscomb, J. D., Thomas, D. D.
Biophysical Society National Meeting – 2003 “Fluorescence studies of the component interactions in Methane Monooxygenase from M. trichosporium OB3b” Popescu, C.V., Lipscomb, J.D., Thomas, D.D. Biophys. J. Abstracts.
International Conference for Bioinorganic Chemistry – ICBIC 11 - Florence, Italy, 2001 “Mössbauer and EPR Studies of the Photoactivation of Nitrile Hydratase” - Popescu, C.V., Münck, E., Fox, B. G, Sanakis, Y., Cummings, J. G., Turner, I. M., Jr., Nelson M. J.
National Science Foundation Award - NSF-MCB Standard Grant starting in 2021
Project Title: Collaborative Research: The ferric uptake regulator (Fur) regulates intracellular iron homeostasis via reversible binding of a [2Fe-2S] cluster in Escherichia coli (Collaborative research with Dr. Huangen Ding, at Louisiana State University, Baton, Rouge, LA)
Past Awards
2014-2017: National Science Foundation – RUI: Mössbauer Studies of Iron Containing Model complexes and enzymatic active sites ($ 189,000) – CHE-1445959;
2013-2014: National Science Foundation – RUI: Mössbauer Studies of Iron Containing Model complexes and enzymatic active sites - CHE-1307650
2010-2014: National Science Foundation – RUI: Mössbauer Studies of Iron Containing Model complexes and enzymatic active sites ($ 165,000) – CHE-0956779
2004-2007: National Science Foundation – Major Research Instrumentation Award for Acquisition of a Mössbauer Spectrometer at Ursinus College ($124,000) – MRI-0421116
2002-2003: NIH Ruth Kirschstein National Research Service Award for post-doctoral research – Structural Dynamics of Methane Monooxygenase by Nitroxide-EPR and Fluorescence Energy Transfer (FET).